BD Difco Freunds Complete Adjuvant, 6x10mL ampules, 263810
BD Difco Freund's Complete Adjuvant, pack of 6x10mL glass ampules.
BD Difco Catalog No. 263810
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BD DIFCO Freund's Complete Adjuvant (263810)
This world renowned product is a suspension of desiccated Mycobacterium butyricum in a mixture of paraffin oil and an emulsifying agent (mannide monooleate). It is used in the preparation of antigen-adjuvant emulsions used in immunological studies with laboratory animals.
Formulation per 10mL ampule:
Mannide Monooleate (1.5mL)
Paraffin oil (8.5mL)
Mycobacterium butyricum (5mg)
Sold as a pack of 6x10ml
BD Difco Catalog No. 263810
Manufacturer : Becton Dickinson (BD/Difco) Becton, Dickinson and Company USA
BD Difco Complete Freund's Adjuvant 263810 (CFA) is used as a standard adjuvant for the induction of experimental autoimmune encephalomyelitis (EAE), the most commonly used animal model in multiple sclerosis studies. Complete Freunds Adjuvant induces glial activation and neuroinflammation on its own and provokes pain. Complete Freund's Adjuvant contains Mycobacteria, an immune response against bacterial antigens is induced in parallel to the response against central nervous system antigens. Thus, CFA can be considered as a confounding factor in multiple sclerosis-related studies performed on EAE. For additional information on how Complete Freunds Adjuvant is used in research, see: https://pubmed.ncbi.nlm.nih.gov/38426111/
Specific References
- MPN
- 263810